Current Research Activities Synthesis of An Inhibitor of the Sodium Pump Obtained From Human Placenta Molecular Modelling and Visualisation of Chemical Structures Molecular Modelling & Structure-Activity Relationships of 4-Amino-mono and bis-Quinolines: Novel Antimalarials with Activity in vitro and in vivo Molecular Modelling & Structure-Activity Relationships of pyronaridine: Novel Benz-naphthyridine Antimalarials with Activity in vitro and in vivo Correlation of Spectral, Molecular Modelling with Biological Activity of Certain Trioxanes related to Qinghaosu Synthesis of Unusual Trifluralin-Phenylenediamine dimers: Novel Scafolds leading to Compound with Leprostatic and Anticancer Activity Reactions exploiting Ortho-Claisen Rearrangement of Allyl Ethers: Synthesis of Benzofurans and Benzopyrans in Near Superacid Media Synthesis of Dimeric Benzodiazepines Critical Reviews of Medicines in Current Use

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Optimisation of the Kelly Process Research team: F. M. D. Ismail and Dr N S Isaacs Programme of studies: Our replacement of the highly polluting Kelly Process with an atom efficient synthesis of mercaptobenzothiazole (MBT), an accelarator used in world-wide rubber production, has significantly reduced both airborne and landfill pollution in the US. More Information HTML/PDF Historical Information on accelerators

Spacefilling (CPK) structure of the rubber additive MBT (Mercaptobenzthaiazole) Molecules Maintained By W.A.Moule (B.Sc, Hons), Head of Molecular Modelling, Medicinal Chemistry Research Group.