Essential Statistics for the Pharmaceutical Sciences - Phil Rowe - Wiley - 2007 (ISBN 978-0-470-03468-2)

Data sets from the book | Instructions for performing tests using stats packages | Additional topics


Data sets from the book (Provided as MicroSoft XL spreadsheets)

Table 2.1Potency of 10 batches of vaccine (Units/ml)
Table 2.2 Ranked times taken to open a child-proof container and calculation of the median
Table 2.3 Individual changes in a global assessment variable following treatment with an anti-inflammatory (60 patients)
Table 2.4 Erythromycin contents of 10 tablets from an Alpha and a Bravo tabletting machine
Table 2.5 Ranked half-lives for two steroids
Table 4.1 Erythromycin contents (mg) for 2 random samples of tablets (both from an Alpha machine)
Table 4.2 Erythromycin contents (mg) for 2 random samples of tablets (One from and Alpha and the other from a Bravo machine)
Table 5.1 Imipramine content (mg) of 9 randomly selected tablets
Table 5.3 Tetracyline content (%w/w) in 8 samples taken from a single batch
Table 6.1 Clearance of theophylline (ml/min/kg) for control subjects and for those pre-treated with rifampicin
Table 9.1 Areas Under the Curve (AUCs) for old and new formulations of propranolol
Table 10.1 Clearance (ml/min/kg) of an amphetamine with and without urinary acidification
Table 12.1 Effects of an alleged weight reducing drug on subjects' weights
Table 13.1 Effect of catalyst on yield (Percentage of theoretical maximum)
Table 13.7 Effects of catalyst and mixing method on yield (Percentage of theoretical maximum)
Table 13.12 Effects of punch design and compression force on tablet strength (MPa)
Table 14.1 Heights at which leaves were growing in the trees (M) and drug content mg/100g dry leaf
Table 14.3 Rainfall at the growing site and concentration of fungal toxin in nuts
Table 14.5 Quantity of PABA and resultant absorption at 510nm
Table 14.6 Rainfall, temperature, sunshine and wind speed at growing sites and concentration of fungal toxin in nuts
Table 16.1 A contingency table showing the effect of IUD design upon the number of women where the device was expelled
Table 16.3 Attendance at a diabetes clinic following various additional reminders
Table 17.1 Production of a toxic metabolite (μg) from an analgesic drug in smokers and non-smokers
Table 17.5 Scores for effectiveness of placebo/active analgesic
Table 17.6 Haemoglobin levels (g/L) in a group of vegans before and after vitamin B12 supplementation
Table 17.7 Pain scores with three different analgesics
Table 17.9 Educational levels and knowledge scores after reading revised information leaflet
Table 17.11 Gastro-intestinal discomfort scores in patients taking two different analgesic drugs
Table 19.1-4 Analyses of the influences of age and health status on opinions concerning a liberalised supply of emergency contraception

Instructions for performing tests

Select statistical package...
Minitab |SPSS | R


Minitab instructions

Absolute basics - How to use the programme
Confidence interval for a proportion
Confidence interval for the difference between two proportions
Confidence interval for the mean
Confidence interval for the mean (One-sided)
Confidence interval for the mean (With log transformation)
Contingency chi-square test
Correlation analysis (Pearson)
Correlation analysis (Spearman)
Descriptive statistics
Dunnett's test
Goodness-of-fit chi-square test
Kruskal-Wallis test
Mann-Whitney test
Median
Mean
Multiple regression analysis
One-way analysis of variance
Paired t-test
Pearson correlation analysis
Quartiles
Regression analysis
Sample size for contingency chi-square test
Sample size for two-sample t-test
Spearman correlation analysis
Standard deviation
Standard error of the mean (SEM)
Tukey's test
Two-sample t-test
Two-sample t-test (one-sided)
Two-way analysis of variance
Wilcoxon paired samples test

SPSS instructions

Absolute basics - How to use the programme
Confidence interval for a proportion
Confidence interval for the difference between two proportions
Confidence interval for the mean
Confidence interval for the mean (One-sided)
Confidence interval for the mean (With log transformation)
Contingency chi-square test
Correlation analysis (Pearson)
Correlation analysis (Spearman)
Descriptive statistics
Dunnett's test
Kruskal-Wallis test
Mann-Whitney test
Median
Mean
Multiple regression analysis
One-way analysis of variance
Paired t-test
Pearson correlation analysis
Quartiles
Regression analysis
Sample size for contingency chi-square test
Sample size for two-sample t-test
Spearman correlation analysis
Standard deviation
Standard error of the mean (SEM)
Tukey's test
Two-sample t-test
Two-sample t-test (one-sided)
Two-way analysis of variance
Wilcoxon paired samples test

R instructions

Dr Paško Konjevoda of the NMR Center, Ruder Boskovic Institute, Zagreb, Croatia has very kindly published full instructions for carrying out all the analyses from the book, using the R statistical package. A brief introduction and full instructions are available.

Additional topics

Data presentation
Fixed and random factors
McNemar's test
Paired t-tests based on percentage change
Selecting a statistical method
Skewness and kurtosis
Testing for a normal distribution - why you shouldn't do it